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VIGABATRIN
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API and Intermediates
- Product description
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Product Intro
Vigabatrin, the gamma-vinyl derivative of GABA, is a new anticonvulsant reportedly effective in the treatment of intractable seizures unresponsive to currently available therapy. Mechanistically vigabatrin is a potent irreversible GABA aminotransferase inhibitor which modifies the enzyme's active-site by Michael addition. Other potential indications have been suggested for vigabatrin, including depression and schizophrenia.
Function
Vigabatrin is a selective GABA transaminase inhibitor.
Application
1.antineoplastic
2.antibiotic
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