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Oxaliplatin
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- Product description
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PRODUCT INTRO
Oxaliplatin, also known as loxadine and oxaliplatin, is a platinum derivative. Clinically, it is used to treat patients with colorectal cancer metastasis after fluorouracil treatment failure. It can be used alone or in combination with fluorouracil. It is the third generation of new platinum antitumor compound after cisplatin and carboplatin. It is also the only platinum drug with significant activity for colorectal cancer so far. The principle of action is to produce alkylation conjugates to act on DNA, form intra chain and inter chain crosslinks, and inhibit DNA synthesis and replication. It also inhibits the proliferation of ovarian cancer and melanoma cell lines.
FUNCTION
Clinically, it can be used alone or in combination with fluorouracil to treat patients with colorectal cancer metastasis after failure of fluorouracil treatment. It is the third generation of new platinum antitumor compounds after cisplatin and carboplatin. It is also the only platinum drug with significant activity for colorectal cancer so far
APPLICATION
1. Colorectal cancer.
2. Ovarian cancer.
3. it is also effective for gastric cancer, breast cancer, non-small cell lung cancer and non Hodgkin's lymphoma.
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