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Tenofovir
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API and Intermediates
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Product Intro
Nucleoside antiviral drugs are synthetic nucleotide analogues. Their chemical structure is simple and easy to modify and synthesize. They are the fastest developing antiviral drugs. A series of new antiviral drugs with high efficiency and low toxicity nucleoside analogues have been developed and have been used or will be used in the treatment of HIV infection and HBV infection. Nucleoside analogues can be divided into purines and pyrimidines from the drug structure type. According to the drug effect, they are mainly divided into antiretroviral (RT) drugs, anti hepatitis virus drugs, anti herpesvirus drugs and anti other virus drugs.
FunctionTenofovir is an acyclic nucleoside antiviral drug, which can inhibit HBV multienzyme polymerization and HIV reverse transcriptase. Tenofovir bisphosphate, the active component of tenofovir, can inhibit viral polymerase by directly competitive combination with natural deoxyribose substrate and terminate the chain by inserting into human DNA.
ApplicationIt is used to treat HIV and HBV infection. This product and other reverse transcriptase inhibitors are used in the treatment of HIV-1 infection and hepatitis B.
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