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Pralidoxime lodide
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API and Intermediates
- Product description
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Product Intro
Phosphorous iodide is defined as yellow granular crystal or crystalline powder, odorless, bitter in taste and easy to deteriorate when exposed to light. Soluble in water and hot ethanol, slightly soluble in ethanol. The aqueous solution is stable, but its properties in alkaline solution are not stable enough. It is easy to hydrolyze into cyanide, which is highly toxic, so it is forbidden to be compatible with alkaline drugs.
Function
Phosphatidyl iodide, as a revival agent of cholinesterase of quaternary ammonium salt, can relieve the nicotine-like symptoms of organophosphorus poisoning, and quickly relieve muscle tremor and bronchospasm. It can be used for the rescue of acute organophosphorus poisoning, and has a good effect on sarin, parathion, phosphorus absorption, thiophosphate, malathion and ethion poisoning, but has a poor effect on tabun, dichlorvos and trichlorfon, and carbamate insecticides, diazinon, cyanophos, propylamine chlorophosphate and octa.
Application
It can revive the cholinesterase activity inhibited by acute organophosphorus pesticides in different degrees and is used to save the poisoning of many organophosphorus pesticides. However, the poisoning effect on malathion, trichlorfon, dichlorvos, dimethoate, methyl fluorophosphate, propylamine fluorophosphate and octamethyl phosphate is poor; Cholinesterase inhibited by carbamate insecticides has no revival effect.
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