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![(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride](/npublic/img/s.png "(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride")
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(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride
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API and Intermediates
- Product description
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Product Intro
This is the intermediate of irutinib. Ibrutinib is a Bruton tyrosine kinase (Btk) inhibitor for the treatment of chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL).
FunctionIrutinib can combine with Btk, which is necessary for the formation, differentiation, information transmission and survival of B lymphocytes, irreversibly inhibit the activity of BTK and effectively inhibit the proliferation and survival of tumor cells
ApplicationIbrutinib is an inhibitor of BTK kinase. It can covalently bind with cysteine residues in the active center of BTK, so as to inhibit the activity of B cells. It has a significant effect on B-cell lymphoma, especially for patients with a variety of advanced lymphomas that are difficult to relapse.
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