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Abiraterone and Intermediates

Category:

API and Intermediates

Summary:

Abiraterone, also known as 17 - (3-pyridyl) androsterol-5,16-diene-3 β- Alcohol is a synthetic steroid CYP17A1 inhibitor. It is the active metabolite of abiraterone acetate, the ester and prodrug of abiraterone.

CAS:

154229-19-3

Standard:

Enterprise

Purity:

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Keywords:

API and Intermediates

Product description

Product Intro
Abiraterone is a targeted cytochrome CYP17 (17) α- Hydroxylase / c17,20-lyase) inhibitor produces abiraterone after hydrolysis. Abiraterone acetate inhibits cytochrome CYP17 through chemicalbook, thereby reducing the production of testosterone. It is suitable for the treatment of patients with castrated refractory prostate cancer (CRPC) who have received previous chemotherapy containing docetaxel.
Function
Abiraterone is an oral inhibitor of cytochrome oxidase P450 (CYP450) C17. It reduces androgen levels by inhibiting cyp450c17, a key enzyme in androgen synthesis, and inhibits androgens in testis and other parts of the body.
Application
Abiraterone is only approved for the treatment of paclitaxel chemotherapy refractory CPRC

Dutasteride and Intermediates

Abiraterone acetate

Dutasteride and Intermediates

Abiraterone acetate

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Abiraterone and Intermediates

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