Abiraterone and Intermediates

Abiraterone, also known as 17 - (3-pyridyl) androsterol-5,16-diene-3 β- Alcohol is a synthetic steroid CYP17A1 inhibitor. It is the active metabolite of abiraterone acetate, the ester and prodrug of abiraterone.

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1000

CAS:

154229-19-3

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Product description

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Product Intro

Abiraterone is a targeted cytochrome CYP17 (17) α- Hydroxylase / c17,20-lyase) inhibitor produces abiraterone after hydrolysis. Abiraterone acetate inhibits cytochrome CYP17 through chemicalbook, thereby reducing the production of testosterone. It is suitable for the treatment of patients with castrated refractory prostate cancer (CRPC) who have received previous chemotherapy containing docetaxel.

Function

Abiraterone is an oral inhibitor of cytochrome oxidase P450 (CYP450) C17. It reduces androgen levels by inhibiting cyp450c17, a key enzyme in androgen synthesis, and inhibits androgens in testis and other parts of the body.

Application

Abiraterone is only approved for the treatment of paclitaxel chemotherapy refractory CPRC

Keyword:

Abiraterone

CAS 154229-19-3

Abitron

Steroid hormone

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Dutasteride and Intermediates

Abiraterone acetate