Baclofen
Product Intro
Baclofen, trade name: leoresin, chemical name: β- 4-Chloro-phenyl- γ- Aminobutyric acid, yes γ- The substituted derivatives of aminobutyric acid are skeletal muscle relaxants and sedatives acting on the brain and spinal cord of the central nervous system. This product inhibits the release of excitatory amino acids such as glutamate and aspartate by activating GABA receptors, so as to inhibit the transmission of monosynaptic and polysynaptic reflex in the brain and spinal cord of the central nervous system, so as to play a spasmolysis role.
Function
Its main function is to excite GABA receptors, inhibit the release of excitatory amino acids such as aspartate and glutamate through synapses, make potassium and calcium ions in neurons outflow, produce hyperpolarization, reduce the transmission of monosynaptic and polysynaptic reflex, promote the normal activity of intermediate neurons and reduce the activity of motor neurons, So as to alleviate the spasticity of skeletal muscle caused by pyramidal tract damage, reduce muscle tension and promote the recovery of motor function.
Application
1. Treat hemiplegia caused by cerebrovascular diseases. 2. Treat intractable hiccup and neuropathic pain. 3. Treat dysfunctional micturition and micturition dysfunction after spinal cord injury. 4. Treatment of acute attack of lumbar disc herniation. 5. Treat spinal cord injury spasm. 6. Intrathecal injection therapy, high-dose injection of baclofen can alleviate the spasm caused by spinal cord injury in a short time.
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