Cilastatin is a synthetic dehydropeptidase inhibitor. By recycling blood, the blood concentration of antibiotics is increased and the half-life is prolonged, so that the antibacterial activity is enhanced.
This product is used in combination with carbapenem antibiotic imine. Because of its specific inhibition on renal peptidase, the latter is protected from the degradation of renal peptidase and the activity of imine coordination is improved.
It is applicable to various infections caused by sensitive strains: lower respiratory tract infection, complex urinary tract infection and upper urinary tract infection, abdominal and pelvic infection, blood flow infection, bone and joint infection, skin and soft tissue infection, infective endocarditis, etc.