Cytarabine
PRODUCT INTRO
Cytarabine is a purine nucleoside antiviral drug extracted from Streptomyces culture solution and then prepared by chemical synthesis. It is a white crystalline powder. It is a pyrimidine antimetabolic drug mainly Acting on the s proliferation phase of cells. It has a significant inhibitory effect on DNA viruses such as poxvirus, herpesvirus and adenovirus. It is mainly used for acute leukemia. It has the best curative effect on acute myeloid leukemia and has a certain curative effect on malignant lymphoma, lung cancer, digestive tract cancer and head and neck cancer.
FUNCTION
It is mainly used in acute leukemia. It is a nucleoside synthesized from cytosine and arabinose. It can inhibit the synthesis of cell DNA and interfere with cell proliferation, so as to achieve the effect of anti-tumor.
APPLICATION
The drug is metabolized in liver, kidney and other tissues, and is rapidly deamination by cytosine deaminase to form inactive uracil arabinoside. In cerebrospinal fluid, due to the low content of the deaminase, its deamination effect is slow.
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