Clomastine fumarate is a powerful, long-acting and highly selective histamine H1 receptor blocker. It has no inhibitory effect on cholinergic receptor of central nervous system, no sedative and sleepy effects. It is mostly used for allergic rhinitis, anti allergic asthma, urticaria, eczema, dermatitis and skin pruritus.
It selectively acts on H1 receptor, prevents histamine from acting on target cells, reduces capillary permeability, and has little effect on 5-hydroxytryptamine (5-HT) or choline. Clomastine has strong antipruritic effect and takes effect quickly. The efficacy can last for 12 hours.
rhinallergosis; Allergic diseases such as urticaria, eczema and skin pruritus; It can also be used for anti allergic treatment of bronchial asthma. It can also be used to treat runny nose and sneezing caused by the common cold.