Product Intro

Ornidazole is the third generation of nitroimidazole drugs, which has obvious antibacterial advantages over metronidazole and Tinidazole. The efficacy of ornidazole lasts for a long time, and its plasma elimination half-life is 14.4 hours, which is higher than 8.4 hours of metronidazole and 12.7 hours of tinidazole. Therefore, it can reduce the number of medication for patients and be more convenient to use. It acts on the DNA of anaerobic bacteria, amoeba, Giardia and Trichomonas, breaks its spiral structure or prevents its transcription and replication, resulting in the death of pathogenic bacteria. The peak plasma concentration was reached 2 hours after oral administration, and the bioavailability was about 90%.

Function

In vivo, the drug is a drug prototype or active metabolite with cytotoxic effect. It acts on the DNA of anaerobic bacteria, amoeba, Giardia and Trichomonas, breaks its spiral structure or blocks its transcription and replication, resulting in its death, so as to achieve the purpose of antibacterial and antigenic biomass.

Application

1. Male and female urogenital tract infection caused by Trichomonas.

2.阿米巴原虫引起的肠、肝阿米巴虫病(包括阿米巴痢疾、阿米巴肝脓肿)。

2. Intestinal and hepatic amoebiasis caused by amoeba protozoa (including amoeba dysentery and Amoeba liver abscess).

3.贾第鞭毛虫病。

3. Giardiasis.

4.厌氧菌感染：如败血症、脑膜炎、腹膜炎、手术后伤口感染、产后脓毒病、脓毒性流产、子宫内膜炎以及敏感菌引起的其他感染。

4. Anaerobic bacterial infection: such as sepsis, meningitis, peritonitis, postoperative wound infection, postpartum sepsis, septic abortion, endometritis and other infections caused by sensitive bacteria.

5.预防各种手术后厌氧菌感染。

5. Prevent anaerobic infection after various operations.